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Take two to three tablets daily ,one with each meal or as directed by a health care professional store in cool ,dry place , keep out of reach of children.


Glucosamine sulfate

Glucosamine sulfate is a naturally occurring chemical found in the human body. It is in the fluid that is around joints. Glucosamine is also found in other places in nature. For example, the glucosamine sulfate that is put into dietary supplements is often harvested from the shells of shellfish. Glucosamine sulfate used in dietary supplements does not always come from natural sources. It can also be made in a laboratory.

Glucosamine sulfate is commonly used for arthritis. Scientists have studied it extensively for this use. It is most often used for a type of arthritis called osteoarthritis. This is the most common type of arthritis.

Glucosamine is also in some skin creams used to control arthritis pain. These creams usually contain camphor and other ingredients in addition to glucosamine. Researchers believe that any pain relief people may experience from these creams is due to ingredients other than glucosamine. There is no evidence that glucosamine can be absorbed through the skin

Osteoarthritis. Most research on glucosamine sulfate has measured its effectiveness on osteoarthritis of the knee. However, there is some evidence that it might also help osteoarthritis of the hip or spine.

Some research suggests that glucosamine reduces pain of osteoarthritis in the knee about as well as the over-the-counter pain reliever acetaminophen (Tylenol). It also seems to reduce pain about as much as the nonsteroidal anti-inflammatory drugs (NSAIDs) ibuprofen (Motrin, Advil) and piroxicam (Feldene). But there is a difference between glucosamine sulfate and these drugs in the time it takes to reduce pain. The NSAIDs, such as Motrin, Advil, and Feldene, relieve symptoms and reduce pain usually within about 2 weeks, but the glucosamine sulfate takes about 4-8 weeks.

Glucosamine sulfate does not seem to decrease pain in everyone who takes it. Some people get no benefit. Some research shows that glucosamine sulfate might not work very well for people with more severe, long-standing osteoarthritis, or for people who are older or heavier.

In addition to relieving pain, glucosamine sulfate might also slow the breakdown of joints in people with osteoarthritis who take it long-term. Some researchers hope that glucosamine sulfate might keep osteoarthritis from getting worse as quickly as it otherwise might. There is some evidence that people who take glucosamine sulfate might be less likely to need total knee replacement surgery.

Are there safety concerns?

Glucosamine sulfate is LIKELY SAFE when used appropriately by adults.

Glucosamine sulfate can cause some mild side effects including nausea, heartburn, diarrhea, and constipation. Uncommon side effects are drowsiness, skin reactions, and headache. These are rare.

Special precautions & warnings:

Pregnancy or breast-feeding: There is not enough reliable scientific information available to know if glucosamine sulfate is safe to take during pregnancy or while breast-feeding. Until more is known, do not take glucosamine sulfate while pregnant or breast-feeding.

Asthma: There is one report linking an asthma attack with taking glucosamine. It is not known for sure if glucosamine was the cause of the asthma attack. Until more is known, people with asthma should be cautious about taking products that contain glucosamine.

Diabetes: Some early research suggested that glucosamine sulfate might raise blood sugar in people with diabetes. However, more recent and more reliable research now shows that glucosamine sulfate does not seem to affect blood sugar control in people with type 2 diabetes. Glucosamine appears to be safe for most people with diabetes, but blood sugar should be monitored closely.


turmeric is a plant. You probably know turmeric as the main spice in curry. It has a warm, bitter taste and is frequently used to flavor or color curry powders, mustards, butters, and cheeses. But the root of turmeric is also used widely to make medicine.

Turmeric is used for arthritis, heartburn (dyspepsia), stomach pain, diarrhea, intestinal gas, stomach bloating, loss of appetite, jaundice, liver problems and gallbladder disorders.

It is also used for headaches, bronchitis, colds, lung infections, fibromyalgia, leprosy, fever, menstrual problems, and cancer. Other uses include depression, Alzheimer’s disease, water retention, worms, and kidney problems.

Some people apply turmeric to the skin for pain, ringworm, bruising, leech bites, eye infections, inflammatory skin conditions, soreness inside of the mouth, and infected wounds.

In food and manufacturing, the essential oil of turmeric is used in perfumes, and its resin is used as a flavor and color component in foods.

Are there safety concerns?

Turmeric is LIKELY SAFE when used appropriately by adults.

Turmeric usually does not cause significant side effects; however, some people can experience stomach upset, nausea, dizziness, or diarrhea.

In one report, a person who took very high amounts of turmeric, over 1500 mg twice daily, experienced a dangerous abnormal heart rhythm. However, it is unclear if turmeric was the actual cause of this side effect. Until more is known, avoid taking excessively large doses of turmeric.

Special precautions & warnings:

Pregnancy and breast-feeding: Taking turmeric by mouth in medicinal amounts is LIKELY UNSAFE in pregnancy. It might promote a menstrual period or stimulate the uterus, putting the pregnancy at risk. Don’t take turmeric if you are pregnant.


Bromelain is a natural enzyme found in the stem and fruit of the pineapple, a tropical fruit native to Central and South America. Bromelain supplements are promoted as an alternative remedy for various health problems including joint inflammation and cancer.

Some small studies have suggested bromelain may help reduce the ill effects of some types of chemotherapy.

Early studies have also looked at the possible use of bromelain for tissues damaged by burns, as a digestive enzyme, to reduce arthritis pain, and for treating bowel inflammation or diarrhea. However, there are no available scientific studies that have looked at whether bromelain shrinks tumors, improves comfort, or extends the life of people with cancer.

How is it promoted for use?

Proponents claim bromelain reduces the swelling and inflammation of soft-tissue injuries. Some people also believe that the enzyme helps a number of digestive problems. Practitioners claim bromelain relieves the pain and inflammation caused by joint disorders such as arthritis and that it inhibits cancer cell growth when combined with chemotherapy. There are some who claim that bromelain can “digest fat” and that people who take bromelain pills can lose weight without diet or exercise. Some supporters also state that bromelain fights bacterial and viral infections

What does it involve?

Although small amounts of bromelain can be obtained naturally by eating fresh pineapple, some people also use supplements. They are available in capsules, tablets, and ointments in most health food stores and on the Internet. Bromelain is also a common ingredient in vitamins, enzyme blends, and supplements sold for joint health.

What is the history behind it?

Bromelain has been used for hundreds of years in folk medicine as a digestive aid and to treat inflammation and other health problems. Christopher Columbus found pineapples growing on the island of Guadeloupe in 1493 and brought them back to Spain. By the 1600s, they were very popular in Europe. In the sixteenth and seventeenth centuries, the plants were distributed to the Pacific Islands, India, and Africa. Pineapple was first established as a commercial crop in Hawaii in 1885. Recently, bromelain has been investigated for medical uses, including possible anti-cancer activity.


Osteoarthritis (OA) is a disease that causes pain and difficulty moving joints, particularly in the knees, hips, hands, and spine. This fact sheet provides basic information on OA, summarizes scientific research on selected dietary supplements, mind and body practices, and other complementary health approaches that have been studied for OA, and suggests sources for additional information.

Orally and topically, MSM is used for chronic pain, osteoarthritis, joint inflammation, rheumatoid arthritis, osteoporosis, bursitis, tendinitis, tenosynovitis, musculoskeletal pain, muscle cramps, scleroderma, scar tissue, stretch marks, alopecia (hair loss), wrinkles, protection against sun/wind burn, eye inflammation, oral hygiene, periodontal disease, wounds, cuts, and abrasions/accelerated wound healing. Orally, MSM is also used for relief of allergies (allergic rhinitis, allergic sinusitis, allergy-induced asthma, inhalant allergens, environmental allergens), drug hypersensitivity, gastrointestinal upset, chronic constipation, gastric hyperacidity, ulcers, diverticulosis, premenstrual syndrome (PMS), mood elevation, obesity, poor circulation, hypertension, and elevated serum cholesterol. It is also used orally for diabetes mellitus type 2 (NIDDM), interstitial cystitis, hepatic dysfunction, Alzheimer’s disease, snoring, lung dysfunction including emphysema and pneumonia, chronic fatigue syndrome, autoimmune disorders (systemic lupus erythematous), HIV infection and AIDS, and cancer (breast cancer and colon cancer). Other oral uses of MSM include eye inflammation, mucous membrane inflammation, myositis ossificans generalis, temporomandibular joint dysfunction, leg cramps, connective tissue disorders, migraine, headaches, hangover, parasitic infections of the intestinal and urogenital tracts including Trichomonas vaginalis and Giardia, Candida albicans and other yeast infections, insect bites, radiation poisoning, and as an immunostimulant.


Papain belongs to a family of related proteins with a wide variety of activities, including endopeptidases, aminopeptidases, dipeptidyl peptidases and enzymes with both exo- and endo-peptidase activity.

Members of the papain family are widespread, found in baculovirus, eubacteria, yeast, and practically all protozoa, plants and mammals

PAPAIN an enzyme that can dissolve or degrade the proteins collagen and elastin to soften meat and poultry tissue. It is derived from the tropical papaya tree and is used as a meat tenderizer.

Papain is taken from the fruit of the papaya tree. It is used to make medicine.

Papain is used for pain and swelling (inflammation) as well as fluid retention following trauma and surgery. It is used as a digestive aid and for treating parasitic worms, inflammation of the throat and pharynx, shingles (herpes zoster) symptoms, ongoing diarrhea, hay fever, runny nose, and a skin condition called psoriasis. Papain is also used along with conventional treatments for tumors.

Some people apply papain directly to the skin to treat infected wounds, sores, and ulcers.

In manufacturing, papain is used in cosmetics, toothpaste, enzymatic soft contact lens cleaners, meat tenderizers, and meat products.

Salix alba

Salix alba (white willow) is a species of willow native to Europe and western and central Asia.The name derives from the white tone to the undersides of the leaves.

Willow bark is used to ease pain and reduce inflammation. Researchers believe that the chemical salicin, found in willow bark, is responsible for these effects. However, studies show several other components of willow bark, including plant chemicals called polyphenols and flavonoids, have antioxidant, fever reducing, antiseptic, and immune boosting properties. Some studies show willow is as effective as aspirin for reducing pain and inflammation (but not fever), and at a much lower dose. Scientists think that may be due to other compounds in the herb.

Willow bark appears to be effective for back pain. In a well-designed study of nearly 200 people with low back pain, those who received willow bark experienced a significant improvement in pain compared to those who received placebo. People who received higher doses of willow bark (240 mg salicin) had more significant pain relief than those who received low doses (120 mg salicin).

Several studies show that willow is more effective at reducing pain from osteoarthritis than placebo. In a small study of people with osteoarthritis of the neck or lower back, those who received willow bark experienced significant improvement in symptoms compared to those who received placebo. A similar study of 78 patients hospitalized with osteoarthritis of the knee or hip joint found that patients who received willow bark had significant pain relief compared to those who received placebo.

USES: Willow bark has been used as an aspirin substitute for fever, headache, and for reducing swelling (inflammation) and pain caused by arthritis

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